I don't think so, there is fine enough adjustment available to position the handles where you will. I was assuming, if we are using stainless steel or brass, that the splines would have been cast as a piece with the handle? But I suppose this may not be possible mechanically as the splines may need to be machined? My original doorhandles seem to be cast in rubbishmetal (some sort of zinc alloy I think that decays after 20 years).
Incidentally, apologies for my confusion earlier re door handle splines. Splines tubes?? Don't know what I was thinking of! The hollow splines in the window winders are cast in situ of course, less stress on them.