Does a change in weight matter? The answer is yes, but also no.... Here's what I learned from years of working on balancing with both John Cundy, a great engineer, and Luigi De Virgilio, who knew Lancia so so well from his father and family.
The most important thing is that the weights across all the cylinders are the same. That's key. And along with that, the weights of each component (piston, pin, con rod) should also be identical. That's good practice.
So do changes in weights matter? Backing up to basic understandings in balancing, lets remember the separation between rotating and reciprocating masses - with the piston, pin, etc. and the upper part of the connecting rod as reciprocating, and the lower part of the connecting rod and bearing as rotating. This is generally assumed through the industry.
But approximations are used, with the general sense that all the reciprocating parts oscillate as they go up and down (and remember the conrod moves around too) as a single "mass" in space - and they are not. So if you change one component (say different pistons, shorter skirts, etc), and keep the weights all the same, it's possible that the overall center of the reciprocating mass changes. How much does that matter?
The driving part of the balancing equation involves only a percentage of the reciprocating weight for the Lancia narrow Vs, between say roughly 15-25%, (compared to 100% of the rotating weight) so changes in overall reciprocating mass are not so critical; changes in the location of the center of the mass aren't also that significant for these engines (under 5000 rpm typically, especially for older engines.
So yes, changes in the masses matter - the simplest answer is keeping the same total mass as was original, and making sure each component is the same mass for each of the cylinders. Hope this helps!